以NaOH處理鈦合金形成奈米多孔表面之磷灰石沈積研究

Apatite Formation on a Nano-Porous Titanium Alloy Surface Treated with Aqueous NaOH

鄭中孝(Chung-Hsiao Cheng) ； 何文福(Wen-Fu Ho) ； 賴建宏(Chien-Hung Lai) ； 許學全(Hsueh-Chuan Hsu) ； 吳世經(Shih-Ching Wu)

《科學與工程技術期刊》 6卷1期 (2010/03) Pp. 1-7

https://doi.org/10.7117/JSET.201003.0001

摘要

本研究使用一種簡單的化學處理方法於c.p.Ti和Ti-7.5Mo表面製作生物活性薄層。將c.p.Ti和Ti-7.5Mo分別浸泡在60°C之5M或10M濃度的NaOH溶液中24小時，其表面會形成奈米多孔網狀結構。接著將鹼處理後之試片分別浸泡在37°C人工模擬體液中3天、7天及28天，結果顯示鹼處理後的Ti-7.5Mo比c.p.Ti有較快的磷灰石形成能力，且不同濃度的鹼處理也會影響磷酸鈣層的形成速率，且以10M之NaOH進行鹼處理可得到最好的結果。因此，本研究指出以NaOH進行鹼處理可在Ti-7.5Mo製作具生物活性的表面。

關鍵字

鈦合金 ； 鹼處理 ； 生物活性 ； 人工模擬體液

並列摘要

Bioactive coatings on c. p. Ti and Ti-7.5 Mo were prepared by a simple chemical technique. Specimens of these metals were initially immersed in a 5 or 10 M NaOH solution at 60°C for 24 h, thus resulting in the formation of a nano-porous network structure. The specimens were then immersed in simulated body fluid (SBF) at 37°C for 3, 7 and 28 days, respectively. The apatite-forming ability of the alkali-treated Ti-7.5 Mo was higher than that of the alkali-treated c. p. Ti on exposure to 5 or 10 M NaOH aqueous solutions. Moreover, by comparing the effects of different alkali treatment solutions (5 or 10 M NaOH) on the formation and thickness of the calcium phosphate layer, it can be concluded that the best results were obtained by using the 10 M NaOH solution. The results of this study suggest that the alkali treatment of Ti-7.5 Mo by NaOH aqueous solutions is a suitable method for providing bone-bonding ability to a Ti-7.5 Mo surface.

並列關鍵字

titanium alloy ； alkali treatment ； bioactive ； simulated body fluid SBF