This study aims to investigate the roles of two individual difference variables, need for cognition (NFC) and affect intensity (Al), in the persuasion process of various types of humorous ads. The main research questions are (l) how does individual difference moderate the effects of humorous ads? (2) what's the relationship between individual difference and the mediation process of humorous ads? The results show that cognitive humor is most effective to high-NFC consumers, while affective humor enhances high-AI consumer's attitude toward the ad (Aad). The mediator of humorous ad effect is Aad for low-NFC consumers, and cognitive thoughts for high-NFC consumers. For affective-humor and non-humor ads, AI has a indirect effect on Aad and brand attitude through affective response. For cognitive-humor ads, AI has both direct and indirect effects.