Mineral aggregates constitute a large proportion of an asphalt mixture. Gradation, on the other hand, is one of the most important properties of an aggregate blend. Hence, the link between aggregate gradation and hot mix asphalt (HMA) performance is a considerable issue and has been recognized since HMA was first used. Fuller Equation of gradation is one of the best known aggregate grading methods, which is developed in the early 20th century. In this paper, resistance to permanent deformation of mixtures made of Iran Highway Asphalt Paving Code (IHAPC) gradations and mixtures made of Fuller Equation gradations with various ”n” exponents are compared. Optimum bitumen content for each gradation was determined using Marshall Method (ASTM D1559) and HMA specimens were objected to Dynamic Creep Test. Finally, test results showed that all gradations generated by Fuller Equation result in mixtures with more resistance to permanent deformation compared to mixtures made of IHAPC gradations. Even though, for some of the Fuller gradations, due to low bitumen contents, an evaluation of aging and fatigue is recommended.