Isolation of Steroids from Acetone Extract of Ficus iteophylla

I. A. Abdulmalik ； M. I. Sule ； A. M. Musa ； A. H. Yaro ； M. I. Abdullahi ； M. F. Abdulkadir ； H. Yusuf

《British Journal of Pharmacology and Toxicology》 2卷5期 (2011/11) Pp. 270-272

並列摘要

Two steroids were isolated from the leaves of Ficus iteophylla (Family: moraceae) a plant popularly used in African traditional medicine to treat variety of illnesses. The leaf part of the plant was investigated phytochemically using a standard procedure. Schematic fractionation of its ethanol extract by acetone and methanol and subsequent column chromatography of the acetone fraction over silica gel G (60-120) mesh size led to the isolation of 3$-cholest-5-ene-3, 23diol (1) and 24 ethyl cholest-5-ene- 3$-ol (2). The structure of these two compounds was elucidated using ^1H-NMR, ^(13)C- NMR and DEPT analysis. To the best of our search this is the first report on the isolation of these compounds from the leaves of Ficus iteophylla..

並列關鍵字

Ficus iteophylla ； 1: H- NMR ； ^(13): C- NMR, DEPT ； 3$-cholest-5-ene-3 ； 23diol ； 24 ethyl cholest-5- ene-3$-ol