- 期刊
- OpenAccess
Pregnancy Complicating Primary Mediastinal Large B-cell Lymphoma: A Case Report and Literature Review
妊娠合併原發性縱膈腔大B細胞淋巴瘤：一病例報告及文獻回顧
摘要
妊娠期間合併惡性腫瘤的機率約為每一千個活產中有一位，而其中血液淋巴瘤於過去幾年間有逐漸增加之趨勢。血液淋巴瘤為懷孕期間第四常見之癌症，而其中大部分為何杰金氏淋巴瘤。原發性胸膈腔大B細胞淋巴瘤是一非常罕見之非何杰金氏淋巴瘤。其治療方式大部份來自個人治療經驗。非何杰金氏淋巴瘤合併妊娠於臨床上通常較何杰金氏淋巴瘤更加晚期及廣泛性擴散，因此除了臨床上問題外還合併醫療倫理之難題。 我們報告了一例妊娠29週合併原發性胸膈腔大B細胞淋巴瘤，發生胎死腹中並因化療而造成之嚴重心臟鬱血性心衰竭。
並列摘要
Pregnancy complicating malignancy occurs 1 in 1000 deliveries. Lymphoma associated pregnancy has become increasing during the past few years and is the fourth most commonly occurred malignancy in pregnancy. Most of the cases reported are Hodgkin's lymphoma. Primary mediastinal large B-cell lymphoma is a rare disease of the subtype of non-Hodgkin's lymphoma. The optimal treatment remains non prospective and mainly dependent upon a personal experience due to its rarity. The issue becomes more complicated as its management involved an ethical issue with the characteristics of the non-Hodgkin's lymphoma being more advanced and wide spread as its counterpart during pregnancy. We report a case of primary mediastinal large B-cell lymphoma associated with pregnancy that result in fetal demise at 29 gestational ages. Severe congested heart failure imposed by the chemotherapy was noted during the treatment period.
延伸閱讀
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