Effect of Aromatherapy on Neuropathic Pain: A Meta-analysis of Randomized Controlled Trials

芳香療法對神經病理性疼痛的影響：隨機對照試驗之薈萃分析

李偵碧(Chen-Pi Li) ； 葉宗勳(Chung-Hsin Yeh) ； 俞瑞庭(Jui-Ting Yu) ； 廖玟潔(Wen-Chieh Liao) ； 蔡如愔(Ru-Yin Tsai)

《童綜合醫學雜誌》 15卷S期 (2021/09) Pp. 31-38

https://doi.org/10.3966/20713592202109150S005

摘要

Purpose: This study aimed to determine the effectiveness of aromatherapy on neuropathic pain severity in people suffering from neuropathy. Design: A systematic literature review and meta-analysis was conducted. Methods: Six databases (PubMed, Scopus, Science Direct, CINAHL, OVID, and The Cochrane Library) were searched for studies published between January 2010 and October 2020. Only randomized controlled trials (RCTs) aromatherapy intervention for people with neuropathic pain were included. Results: This meta-analysis included four RCTs, comprising 246 participants in total. Neuropathic pain was significantly suppressed by aromatherapy intervention in both the massage and non-massage groups. Conclusions: The meta-analysis findings suggest aromatherapy as an effective intervention for people with neuropathic pain. Aromatherapy could be considered an adjuvant in clinical neuropathic pain management for patients needing long-term anti-analgesic drug treatment or patients with neuropathic pain.

關鍵字

aromatherapy ； essential oil ； neuropathic pain ； neuropathy ； allodynia ； hyperalgesia

並列摘要

目的：本研究主要目的是確認芳香療法對緩解神經病理性疼痛的有效性。設計：本研究利用系統性文獻回顧和薈萃分析。方法：本研究檢索六個數據庫（PubMed，Scopus，Science Direct，CINAHL，OVID和Cochrane圖書館），探討2010年1月至2020年10月之間發表的研究。僅收集對神經病理性疼痛患者進行芳香療法干預的隨機對照試驗（RCT）。結果：這項薈萃分析包括四個RCT實驗，總共246名參與者。經過芳香療法干預，無論是按摩組或非按摩組均可顯著緩解神經病理性疼痛。結論：從薈萃分析研究結果，我們認為芳香療法對於神經病理性疼痛患者是一種有效的干預措施。對於需要長期使用鎮痛藥物或患有神經病理性疼痛之患者，芳香療法可被視為臨床神經病理性疼痛管理的輔助藥物。

並列關鍵字

芳香療法 ； 精油 ； 神經病理性疼痛 ； 神經病變 ； 痛覺敏感 ； 痛覺過敏