透過您的圖書館登入
IP:3.89.56.228
  • 期刊

Factors Associated with Low Bone Mineral Density among Taiwanese Women Receiving Health Check-ups

體檢婦女低骨質密度的相關因素

摘要


Objectives: The incidence of osteoporosis has risen with increased life expectancy in recent decades. Osteoporosis-related fractures lead to significant morbidity and mortality and poor functional outcome. The risk of fracture escalates significantly as the bone mineral density (BMD) decreases. We assessed the prevalence of low bone mass in women and its associated factors. Methods: Subjects who had received health check-ups at a teaching hospital in eastern Taiwan were invited to participate in this study. A self-administered questionnaire was used to assess their demographic characteristics, diet, lifestyles, reproductive and medical history. Bone mineral density of the posterior-anterior lumbar spine (L1-L4) was measured by dual energy X-ray absorptiometry. A spinal BMD less than 0.85 g/cm^2 was defined as low BMD(subscript L). Univariate and multiple logistic regression analyses were performed to estimate the association of risk factors. Results: Data on 769 Taiwanese women, aged from 36 to 75 years old, with a mean age of 54.9 years, were included in this study. The mean of BMD(subscript L) significantly decreased after aged 50. The percentage of low BMD(subscript L) was three times higher in postmenopausal women (55.7%) than in their premenopausal counterparts (16.0%). The percentage of osteoporosis (T-score≦-2.5) was about 40% in women from 61~70 years old and 70% in those from 71~75 years old. Among the premenopausal women, three significant factors associated with low BMD(subscript L) were identified: current smoking, low body weight (<49 kg) and an age ≥51 years. For postmenopausal women, vegetarianism and an age≥61 were significant factors associated with low BMD(subscript L). Conclusions: Low BMD(subscript L) is prevalent among pre- and post- menopausal women. Women should be assessed for risk factors of low BMDL and referred for BMD testing as indicated. Quitting smoking and keeping an ideal body weight should be emphasized at consultation. For the vegetarians, adequate nutritional supplements and appropriate bone density evaluation should be provided to avoid the risk of osteoporosis.

並列摘要


Objectives: The incidence of osteoporosis has risen with increased life expectancy in recent decades. Osteoporosis-related fractures lead to significant morbidity and mortality and poor functional outcome. The risk of fracture escalates significantly as the bone mineral density (BMD) decreases. We assessed the prevalence of low bone mass in women and its associated factors. Methods: Subjects who had received health check-ups at a teaching hospital in eastern Taiwan were invited to participate in this study. A self-administered questionnaire was used to assess their demographic characteristics, diet, lifestyles, reproductive and medical history. Bone mineral density of the posterior-anterior lumbar spine (L1-L4) was measured by dual energy X-ray absorptiometry. A spinal BMD less than 0.85 g/cm^2 was defined as low BMD(subscript L). Univariate and multiple logistic regression analyses were performed to estimate the association of risk factors. Results: Data on 769 Taiwanese women, aged from 36 to 75 years old, with a mean age of 54.9 years, were included in this study. The mean of BMD(subscript L) significantly decreased after aged 50. The percentage of low BMD(subscript L) was three times higher in postmenopausal women (55.7%) than in their premenopausal counterparts (16.0%). The percentage of osteoporosis (T-score≦-2.5) was about 40% in women from 61~70 years old and 70% in those from 71~75 years old. Among the premenopausal women, three significant factors associated with low BMD(subscript L) were identified: current smoking, low body weight (<49 kg) and an age ≥51 years. For postmenopausal women, vegetarianism and an age≥61 were significant factors associated with low BMD(subscript L). Conclusions: Low BMD(subscript L) is prevalent among pre- and post- menopausal women. Women should be assessed for risk factors of low BMDL and referred for BMD testing as indicated. Quitting smoking and keeping an ideal body weight should be emphasized at consultation. For the vegetarians, adequate nutritional supplements and appropriate bone density evaluation should be provided to avoid the risk of osteoporosis.

延伸閱讀