食品器具容器包裝中內分泌干擾物質雙酚A之溶出量調查

Survey of Endocrine Disruptor Bisphenol a Leaching from Food Utensils, Containers and Packages

張美華(Mei-Hua Chang) ； 顏維良(Wei-Liang Yan) ； 鄒嘉珊(Chia-Shan Tsou) ； 曾素香(Su-Hsiang Tseng) ； 高雅敏(Ya-Min Kao) ； 闕麗卿(Lih-Ching Chiueh) ； 羅吉方(Chi-Fang Lo)

《食品藥物研究年報》 2期 (2011/12) Pp. 192-200

https://doi.org/10.6945/ARFDR.201112.0194

摘要

Bisphenol A (BPA) is an endocrine disruptor. It is used as monomer of plastic polycarbonate (PC) or additive in other plastic products. If bisphenol A released from daily necessities, such as baby bottles, sports water bottles and all kinds' food containers, would lead to health concerns. One hundred samples including various types of plastic containers were collected from March to October, 2010. Materials identification was conducted by Fourier transform infrared Spectroscopy. Six leaching conditions were applied according to the regulation announced by Department of Health, Executive Yuan. All the dissolutions were analyzed by HPLC on a column of Inertsil ODS-2, using acetonitrile : water (1:1, v/v) as mobile phase and monitored by fluorescence detector at Ex 275 nm and Em 304 nm. Bisphenol A standard in the range of 2-40 ng/mL showed a good correlation (R^2 = 0.9999). Bisphenol A migration was not detected, including 11 pieces of PC and other plastic materials under six leaching conditions (＜ 2 ppb).

關鍵字

雙酚A ； 內分泌干擾物 ； 聚碳酸酯 ； 溶出試驗 ； 高效液相層析法

並列摘要

Bisphenol A (BPA) is an endocrine disruptor. It is used as monomer of plastic polycarbonate (PC) or additive in other plastic products. If bisphenol A released from daily necessities, such as baby bottles, sports water bottles and all kinds' food containers, would lead to health concerns. One hundred samples including various types of plastic containers were collected from March to October, 2010. Materials identification was conducted by Fourier transform infrared Spectroscopy. Six leaching conditions were applied according to the regulation announced by Department of Health, Executive Yuan. All the dissolutions were analyzed by HPLC on a column of Inertsil ODS-2, using acetonitrile : water (1:1, v/v) as mobile phase and monitored by fluorescence detector at Ex 275 nm and Em 304 nm. Bisphenol A standard in the range of 2-40 ng/mL showed a good correlation (R^2 = 0.9999). Bisphenol A migration was not detected, including 11 pieces of PC and other plastic materials under six leaching conditions (＜ 2 ppb).

並列關鍵字

bisphenol A ； endocrine disruptor ； polycarbonate ； migration test ； high performance liquid chromatography