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An Aspergilloma Switched to a Chronic Necrotizing Pulmonary Aspergillosis in a Patient with Pulmonary Tuberculosis and Pneumoconiosis History

麴菌腫塊轉變成慢性壞死性肺部麴菌感染發生在一個有過肺結核及塵肺症的病人

摘要


肺結核是台灣常見的一種疾病。許多的病人會留下肺部開洞性病變。在這些開洞的病人中有一部分人會在開洞中形成麴菌腫塊進一步發展成慢性壞死性肺部麴菌感染。在此我們將報導一位有肺結核及塵肺症病史的病人慢慢發展成慢性壞死性肺部麴菌感染的病例並做一些文獻回顧。

並列摘要


Pulmonary tuberculosis is an endemic disease in Taiwan, and its frequent sequela is cavitation. Some of these patients subsequently develop into chronic pulmonary aspergillosis (CPA). We herein report a case of chronic necrotizing pulmonary aspergillosis, which occurred gradually in a patient with aspergilloma, who also had pulmonary tuberculosis and pneumoconiosis history.

參考文獻


Denning, DW,Pleuvry, A,Cole, DC(2011).Global burden of chronic pulmonary aspergillosis as a sequel to pulmonary tuberculosis.Bull World Health Organ.89,864-72.
Lass-Flörl, C,Roilides, E,Löffler, J,Wilflingseder, D,Romani, L(2013).Minireview: host defence in invasive asper-gillosis.Mycoses.56,403-13.
Nakamota, K,Takayanagi, N,Kanauchi, T,Ishiguro, T,Yanagisawa, T,Sugita, Y(2013).Prognostic factors in 194 patients with chronic necrotizing pulmonary aspergillosis.Intern Med.52,727-34.
Ohba, H,Miwa, S,Shirai, M(2012).Clinical characteristics and prognosis of chronic pulmonary aspergillosis.Respir Med.106,724-9.
Prasad, R,Garg, SR(2009).Progressive increase in cavitation with the evolution of fungal ball: A clue to the diagnosis of chronic necrotizing pulmonary aspergillosis.Lung India.26,95-7.

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