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毛細電泳-質譜儀的最新發展

Recent advances in Capillary Electrophoresis/Electrospray mass Spectrometry

摘要


本文介紹數種主要毛細電泳質譜儀(CE-MS)界面的設計,比較各界面的優缺點、操作上以及使用上的限制。由於電灑法是目前毛細電泳質譜儀主要所使用的離子化方法,因此也針對灑法的原理以及機制作探討。另外,本文也針對毛細電泳質譜儀技術的改進,以及在不同領域上的應用作一概略的介紹。

關鍵字

毛細電泳 質譜 電灑法 界面

並列摘要


In this review, several capillary electrophoresis - mass spectrometry (CE-MS) interfaces based upon electrospray ionization (ESI) are illustrated. The merits, limitations and improvements of these interfaces were compared and discussed in this report. Because the CE-MS interface is most commonly based on ESI, the principle and ionization mechanisms of ESI are also introduced. Several examples were introduced to demonstrate the potential of CE-MS in the areas of environmental, biochemical and medical analysis.

並列關鍵字

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