Industrial robots that perform fixed trajectories are not enough to solve the problems caused by the deviations of workpiece size. To the industry, development of robot manipulators with spatial perception is one of the important tasks. In order to make the robot manipulators sense spatial information, it needs to integrate proper sensors, such as a rotary encoder that can obtain the position of the rotary shaft, a force sensor that can measure the contact force, an image sensor that can capture spatial images, and a laser tracker that can accurately measure distances. This article will separately describe the functionality and effectiveness of the robot manipulators with different sensors.