This paper examines the controversy between eco-centrism and anthropocentrism from the perspective of dialectical centrism in Buddhism. It first briefly analyzes the concept of paţicca-samuppāda (緣起) or Buddhist causality, and pays a special attention to the significance of interdependence and interrelatedness. The paper then proceeds to investigate the idea of universal interdependent-origination in Huayan (華嚴) Buddhism so as to see whether such idea can be applied to indicate the relationship between humanity and nature. By showing the imperfectness of anthropocentrism and the impracticability of eco-centrism, I propose dialectical centrism to deal with the relationship between man and nature, and hence, to solve the tension between anthropocentrism and eco-centrism.