- 期刊
Manic Episode Associated with COVID-19 and Corticosteroids in a Patient with Prior Mild Cognitive Impairment
摘要
Background: COVID-19 infection and its treatment with corticosteroids are associated with various neuropsychiatric complications. An increasing number of studies show that patients with COVID-19 may suffer from psychiatric disorders in acute and subacute phases of the disease. Post-COVID mania and mania associated with corticosteroids are two important complications, which clinicians should be aware. Case: We report a 69-year-old male patient who showed mild confusion and cognitive difficulties in the acute phase of COVID-19.With the addition of dexamethasone 8 mg in the treatment of COVID-19, the patient suffered from euphoria, grandiose delusions, reduced need for sleep and rapid and increased speech. The patient was admitted to the psychiatric inpatient clinic and diagnosed with medication-induced mania. The patient showed significant improvement with 15 mg olanzapine and 1000 mg valproate treatment in a week. Discussion: Increasing number of studies focus on psychiatric complications of COVID-19. Although mania and psychoses are relatively rare complications of COVID-19, they deserve special attention from clinicians. Corticosteroids in COVID-19 treatment increase the risk of such mental disorders. This case shows that patients with COVID-19 should be screened for psychiatric disorders, and the use of corticosteroids in patients with specific risk factors should be evaluated regarding psychiatric complications.
延伸閱讀
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