A multi-objective programming model is used to study the location problem of intelligent express delivery cabinet on campus. Specifically, through the establishment of three objective functions of the minimum operation cost, the shortest distance of customers and the highest score of alternative points, the comprehensive evaluation method is used to establish the evaluation index system of campus intelligent express cabinet surrounding environment satisfaction as the basis of alternative points scoring, and the weight assignment method is used to find the Pareto optimal solution of the model. On this basis, the relevant data of express delivery construction of Chongqing University of Posts and Telecommunications were investigated, and the model was verified by a case study. The location scheme of intelligent express cabinets of Chongqing University of Posts and Telecommunications was obtained, which has reference value for promoting the construction of the intelligent delivery cabinet of the university campus.