Advances in the Pharmacological Mechanism of Polyporus Umbellatus in the Treatment of Chronic Glomerulonephritis

Sitong Liu ； Junjian Xu

《International Core Journal of Engineering》 8卷10期 (2022/10) Pp. 13-18

https://doi.org/10.6919/ICJE.202210_8(10).0003

摘要

Chronic glomerulonephritis is a common glomerular disease in China, which will eventually develop into renal failure, seriously threatening human health and life, and the combination of Chinese and Western medicine has achieved certain curative effects. Modern pharmacological studies have also shown that Polyporus Umbellatus has diuretic, anti-tumour, hepatoprotective, renal protective, immune regulating, anti-infective, anti-mutagenic and anti-fibrotic effects, which have been widely used in clinical practice. However, the application of Polyporus Umbellatus in the treatment of chronic glomerulonephritis has not been systematically elaborated. Through reviewing relevant pharmacological research progress and animal experiments, this study elaborates the pharmacological mechanism of Polyporus Umbellatus in the treatment of chronic glomerulonephritis, showing that Polyporus Umbellatus plays a role in diuresis, renal protection, anti-fibrosis, immunomodulation, anti-mutagenesis and anti-inflammation, aiming to provide a basis for the clinical application of Polyporus Umbellatus in the treatment of chronic glomerulonephritis. The aim is to provide a basis for the clinical application of Polyporus Umbellatus in the treatment of chronic glomerulonephritis.

關鍵字

Chronic Glomerulonephritis ； Polyporus Umbellatus ； Pharmacological Mechanism

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