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  • 學位論文

含鈣磷之氧化鈦陽極膜於人工體液浸泡行為

Simulated Body Fluid Immersion of Calcium- and Phosphorus-containing Anodic Titanium Oxide Film

指導教授 : 林招松

摘要


以微弧氧化法於鈦上所生成之具有多孔性,且富含鈣、磷的氧化鈦陽極膜,具備了可轉變成氫氧基磷酸鈣的成份,且可提昇其在植入生物體內的表現。然而此氧化鈦層具有部份內部缺陷,易導致陽極膜與基材的附著性大幅降低。本研究以定電流的方式,在適當的電解液中對於商用純鈦板進行陽極處理,並進行陽極膜的分析。當陽極電壓較高時,陽極膜將具有較高的鈣、磷含量,但較差的附著性。人工體液的浸泡可以於陽極膜上仿生地生成一主要由磷酸鈣鹽類所組成的沉積層。既有的存在於陽極膜中之鈣、磷成份提供了人工體液內沉積反應的成核位置。因此,搭配人工體液的浸泡,可提高從較低電壓所生成的陽極膜之鈣、磷含量。同時,本研究發現於人工體液浸泡之前,先針對陽極膜進行熱鹼處理,可降低於浸泡人工體液時的反應時間。此結果推論為因熱鹼處理所導致的陽極膜表面改質,在浸泡於人工體液的情況下,會在試片與溶液表面生成一酸鹼值較高,且富含磷酸根離子的區域。在此厚度極低的區域中,人工體液的析出反應可因此被加速。本研究所指出的最佳化製程為對於鈦板進行較低電壓的陽極微弧氧化後,依序進行熱鹼處理及人工體液的浸泡。

並列摘要


Anodic oxidation of titanium in the solution containing calcium and phosphorus compounds can prepare a calcium- and phosphorus- containing oxide film. However, during the galvanostatic anodizing process, a porous inner layer formed prior to sparks and a crater-containing overlay formed with sparks resulted in decrease the adhesion of the anodic film. Calcium and phosphorus were predominantly incorporated in the porous overlay, in which the amorphous region contained more calcium and phosphorus than the crystalline region regardless of the anodizing voltages. Moreover, the ratio of amorphous to crystalline regions in the porous overlay changed insignificantly with anodizing voltage. Therefore, higher anodizing voltage can enhance the calcium and phosphorus contents in the anodic film, yet leads to the adhesion decrease problem. Simulated body fluid (SBF) is an unstable solution with some supersaturated calcium phosphate salts. Pure titanium plates and anodized titanium plates were immersed in SBF, and a layer mainly containing calcium and phosphorus was precipitated on them. The chemical properties of both pure titanium and the anodic film were herein enhanced. The time-consuming SBF precipitation process can be adjusted by alkali- and heat-treatment (AHT) before SBF immersion. Both the AHTed titanium and the anodic film resulted in forming a high-pH zone in the SBF medium, and further accelerated the precipitation process in SBF. Properties of the multi-layer structure on titanium were determined by SEM, cross-sectional TEM, EDS, XRD and the adhesion test in this study.

參考文獻


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