Electron transport through nanoscale systems are often studied in the wide-band limit without taking the memory effect into consideration. In this thesis, we present a novel Floquet approach in electron transport through nanoscale systems beyond the wide-band limit to explore the multi-photon (MP) coherent destruction of tunneling (CDT) with memory effect in the presence of time-dependent driving field. As a case study, the time-averaged current is calculated in an electrode-double quantum dots-electrode system driven by a periodic field using single Lorentzian spectral density function and a detailed analysis is presented to illustrate the origin of MP-CDT as well as the significance of memory effect.