奈米黏土/銀複合物之超疏水抗菌材料

Nanohybridization of Silicate Clay/AgNP for Antimicrobial and Superhydrophobic Functions

蔡國華(Kuo-Hua Tsai)

指導教授 ： 林江珍

國立臺灣大學/工學院/高分子科學與工程學研究所/碩士(2016年)

https://doi.org/10.6342/NTU201601004

摘要

本研究利用層狀的天然黏土，蒙托土來承載奈米銀粒子，研究發現將奈米銀粒子複合於蒙托土上可以提升塗佈於基材上之表面貼附性。與我們實驗室以前發明具有高抗菌性及低毒性重量比7 比93 之奈米矽片銀相比，此奈米黏土/銀複合物塗佈於玻璃及PET 基材上具有5B 之貼附性。其抗菌效果亦被測試，對於大腸桿菌與抗藥性金黃色葡萄球之最小抗菌濃度分別為910 與230 μg/cm2。而在毒性測試(Mouse fibroblasts)中，亦顯示此材料的低毒特性。
此具有抗菌效果，低毒性及高基材附著性之奈米複合物可與環氧樹酯進行固化以控制薄膜之表面粗糙度。而薄膜之表面型態藉由掃描式電子顯微鏡觀察，可以發現蒙托土/銀複合物之表面較純蒙托土粗糙，且樹酯的添加並不會影響其粗糙度。除了控制粗糙度，聚異丁烯胺的使用對於超疏水薄膜的製備亦是重要的因素，因其疏水特性。經溶液塗佈及固化過程可產生具有166 度水接觸角與高基材附著性之高分子複合材薄膜。而奈米黏土/銀複合物的參與改善了以前開發由矽片經過鋁離子交換之材料貼附性不佳的問題。此複合材之奈米黏土/銀複合物與樹酯之重量比由100/0 到30/70 可以完全抑制大腸桿菌與抗藥性金黃色葡萄球的生長。在毒性測試(Mouse fibroblasts)中，亦顯示此材料的低毒特性。此超疏水表面塗佈製程簡單，且可適用於不同表面及各種應用。

關鍵字

奈米黏土 ； 奈米銀粒子 ； 塗佈 ； 附著 ； 抗菌 ； 超疏水

並列摘要

The nanohybridization of the silver nanoparticles and natural clay, MMT was found to enhance the surface adhesive properties of pristine MMT. Compared with the previously developed Ag/NSP with weight ratio of 7/93 which had high antibacterial activity and low cytotoxicity, the Ag/MMT nanohybrid showed high cross-cut adhesive property of 5B on PET and glass substrates, and was measured to have the minimum bactericidal concentration (MBC) of 910 for E.coli and 230 μg/cm2 for MRSA. The nanohybird was found to neglect its cytotoxicity to mammalian cells.
The nanohybrid with high adhesive property, antibacterial activity and low cytotoxicity were allowed to cure with the epoxies for controlling the roughness on the film surface for water-repellency. The surface morphologies were observed by SEM, showing Ag/MMT had a rougher surface morphology than the pristine MMT and the addition of resin didn’t affect the roughness. Besides the control of surface roughness, the use of PIB-amine was another important factor for creating superhydrophobic films due to the hydrophobic property. The solution coating and curing process generated the polymer composite films with a water contact angle of 166o and high cross-cut adhesive properties of 5B on substrates in comparison with the previously developed material from NSP exchanged with Al3+. The involvement of the Ag/MMT nanohybrid improved the surface adhesive properties. The composites with the weight ratios of 100/0 to 30/70 could totally inhibit the cell growth of gram positive MRSA and gram negative E.coli. The composites were found to neglect their cytotoxicity to mammalian cells. Ultimately, the fabrication process of the superhydrophobic surface coating is simple and can potentially be applied to different surface for various applications.

並列關鍵字

silicate clay ； silver nanoparticles(AgNP) ； coating ； adhesion ； antibacterial ； superhydrophobic

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