透過您的圖書館登入
IP:3.129.45.92
  • 學位論文

動脈竇對雙葉瓣以及三葉片心瓣關閉的影響

The effect of the Sinus of valsalva on the closing motion of a bileaflet and a trileaflet

指導教授 : 盧博堅

摘要


現代人的飲食習慣逐漸改變,油脂食物的攝取明顯增加,造成身體上的心血管傷害也越來越大,甚至心血管疾病在2010年已經在國人死亡病因中位居前三名,其中包括主動脈瓣膜受損所產生的心血管疾病,其也是來自於油脂食物攝取過多或不運動所導致。而辦模受損必須在危及生命前動手術置換人工機械心瓣,而某些病患因為心臟瓣膜的疾病而必須進行心臟瓣膜移植手術之時,可能因為手術的錯位導致主動脈竇受損或破損而必須切除主動脈上的竇,使的主動脈剩為圓管狀而非人體原先的主動脈結構,而缺乏主動脈竇的主動脈管會不會影響到血液作用在人工心瓣的壓力、血液通行速度以及在主動脈管流場流動的順暢度則是要討論及研究的主要問題。本實驗利用數值模擬事業軟體fluent,模擬SJM雙葉機械心瓣和TRI三葉機械心瓣在無竇主動脈流場的脈動中探討心瓣開啟和關閉所花費的時間,並和兩種不同的主動脈竇所模擬的流場作數據比對,一種為軸對稱型的主動脈竇,另一種為三個半球型的主動脈竇,希望此研究能夠增加日後的學者對心瓣在不同主動脈竇下更深入的認知,以及在三葉心瓣的研發上有更深遠的助益和進展。

關鍵字

數值模擬 機械心瓣 瓣膜 主動脈

並列摘要


Modern people are gradually changed in eating habits, and more people prefer eating grease food,this inclination could lead to more diseases in cardiovascular.This condition causes damages of aorta valve and must do a artificial mechanical heart valve replacement surgery before life-threatening , and some patients with valvular heart disease must be carried out immediately. When errors occurred during valve replacement surgery and injured the aorta sinus,it must be resect and sew up,and it became like a tube.The aorta with no sinus in body may cause hemolysis and thrombosis when valves are opening and closing.We must analyse what would be happen in very pulsation,so we use the Commercial software Fluent to simulate the aorta pulsation without sinus in bileaf let and trileaflet and to find the differences among the different sinus of aorta. This simulation hopes useful in future study of trileaflet.

並列關鍵字

numerical simulation mechanical heart valve Aorta

參考文獻


27.蔡伯昌, 2012,在不同主動脈形狀下機械心瓣的流動特性, 淡江大學水資源及環境工程學系碩士論文.
29.李德倫, 2012, 雙葉及三葉機械心瓣流場流固耦合數值計算, 淡江大學水資源及環境工程學系碩士論文.
1.Pibarot P, Dumesnil JG:Low-Flow, Low-Gradient Aortic Stenosis With Normal and Depressed Left Ventricular Ejection Fraction. JACC Vol. 60, No. 19, 2012 November 6, 2012:1845–53
3.Simon HA, Dasi LP, Leo H-L, Yoganathan AP: Spatio-temporal Flow Analysis in Bileaflet Heart Valve Hinge Regions: Potential Analysis for Blood Element Damage. Annals of Biomedical Engineering 35: 1333-1346, 2007.
4.Claiborne TE, Slepian MJ, Hossainy S, Bluestein D: Polymeric trileaflet prosthetic heart valves: Evolution and path to clinical reality. Expert Rev Med Devices 9: 577–594, 2012.

延伸閱讀