肥胖者經減重課程後血清生化值及代謝症候群危險因子的影響

The effects of weight control program on serum biochemical characteristics and risk factor for metabolic syndrome in overweight subjects

陳妍蒨(Yen-Chien Chen)

指導教授 ： 徐成金

中山醫學大學/健康管理學院/營養學研究所/碩士(2008年)

https://doi.org/10.6834/CSMU.2008.00020

摘要

近年來國人的肥胖盛行率有逐年增加的趨勢，在許多國家，肥胖症已儼然成為公共衛生上重要的問題。肥胖和許多慢性疾病有關，特別是腹部肥胖，罹患代謝症候群的風險高於一般人，而有代謝症候群者，罹患心血管疾病的危險遠較於沒有代謝症候群者高出許多。以營養科學觀點而言，熱量的攝取與消耗的不平均是造成肥胖的主要原因，故限制熱量的飲食控制與規律的運動，成為體重控制最重要的課題。
本研究以17位肥胖者，體重79.84±19.00公斤，BMI30.36 ±4.84 kg/m2，腰圍93.24±14.37公分，經過8週體重控制計畫後，比較減重前後體組成、血液生化值及代謝症候群指標的變化。結果顯示，在血液生化值方面，總膽固醇、HDL、LDL、GPT和Cr均有顯著的下降；在體組成方面，減重前後體重、BMI、體脂肪、皮下脂肪、內臟脂肪、瘦肉組織、腰圍和臀圍均有顯著性的差異；然而代謝症候群指標則在減重前是代謝症候群組明顯大於非代謝症候群組，減重後代謝症候群之各項指標並無統計上顯著的改變，非代謝症候群組則腰圍及HDL有顯著性的差異。經研究證實，肥胖確實易造成體組成及血液生化值的異常，增加慢性病的罹病率及致死率，若能以飲食控制，配合有氧運動及行為修正，可有效降低體重，改善體組成及血液生化值的異常現象，促進健康。

關鍵字

肥胖者 ； 體重控制計畫 ； 體組成 ； 血液生化值 ； 代謝症候群

並列摘要

The prevalence of obesity is increasing in recent years. It has been important public health problem in many countries. Obesity is associated with risk factors of many diseases. Metabolic syndromes (MS) are linked with central obesity and may cause cardiovascular diseases (CVD). The energy intake and expenditure unbalancedly is the main cause of obesity. The most important of body weight control is to restrict calorie intake, modify dietary manner and keep doing exercise. The purpose of this study evaluated effect of 8-week body-weight-reduction program in 17 obesity subjects with body weight79.84±19.00kg,BMI30.36±4.84kg/m2, waist circumference 93.24±14.37cm,which preceded this approach by comparison of biochemical assessment, anthropometry, body weight and percentage of body fat, between pre and post weight reduction. The results showed that before the weight control program was administrated, After the weight control program, the biochemical characteristics which included total cholesterol,HDL,LDL,GPT and Cr were significantly improved;the body composition which included body weight, BMI, body fat, subcutaneous fat, isceral fat,lean body mass, waist circumference and hip circumference were also significantly improved. However, the improvement on indicators for metabolic syndromes before 8-week body-weight-reduction program is MS higher than, but after 8-week body-weight-reduction program MS subjects is no significantly improved ,non-MS subjects waist circumference and HDL were better than those in MS subjects. In conlusion, obesity could make abnormal of body composition and biochemical characteristics, and consider as a chronic disease with morbidity and motality. It is better to take diet control , exercise and modify intake behavior, could reduce body weight, improve body composition and biochemical characteristics, and more effects of psychological health.

並列關鍵字

obesity ； body-weight-reduction program ； body composition ； biochemical characteristics ； Metabolic syndromes

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