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  • 學位論文

CKD患者經營養介入後之效益分析研究

The study of the benefits analysis after nutrition support on chronic kidney disease (CKD) patients

指導教授 : 徐成金

摘要


臺灣洗腎人口目前居亞洲之冠,營養治療在腎臟保健計劃中亦是重要的一環。本研究的目的是為探討一年兩次的飲食指導介入對於慢性腎臟疾病(CKD, Chronic kidney disease)患者體重、生化數值、熱量及蛋白質的攝取是否有正向的助益。研究方法:由秀傳醫院腎臟科門診隨機篩機101位慢性腎臟病患者,給予一年至少兩次的飲食指導衛教,並評估患者的體重、生化數值及熱量、蛋白質攝取前後之間的變化比較,並再進行相關性迴歸性分析其因子間的相關性是否有顯著性差異。結果:所篩選的慢性腎臟病患者以61-70歲人口最多,佔了35.6% ,其中高血壓及糖尿病患者所佔比例最多。在對慢性腎臟疾病患者做營養介入後發現白蛋白、尿素氮(BUN)、肌酸酐(Cr.)、血紅素(Hb)、尿酸、三酸甘油酯、膽固醇、血磷離子及飲食中蛋白質的攝取在營養介入後呈現顯著性的差異(p<0.001);尿素氮(BUN)、肌酸酐(Cr.)、磷離子及MDRD-GFR等因子經迴歸性分析後發現它們有著顯著性的線性相關,將尿素氮、肌酐酸及磷離子與MDRD-GFR比較發現其線性關係存在著明顯的負相關(p<0.001);而尿素氮與肌酐酸之間的線性關係顯示正相關性。統計方法:pair t-test及regression analysis。結論:營養介入對慢性腎臟疾病患者是具有助益的。

並列摘要


It is a large population of patients with hemodialysis in Taiwan. Nutritional support is important for these patients. This study was aimed to understand the effect of dietary guide twice per year upon nutritional status for these patients in Show-Chung hospital. Results showed after one-year interventional program, albumin, BUN, creatinine, hemoglobin, uric acid, TG, cholesterol, phosphorus and dietary protein were significantly changed (p<0.001), in which MDRD-GFR was negatively correlated with BUN, creatinine and phosphours (p<0.001). This study found that dietary guide for chronic kidney disease patients twice per year was beneficial.

參考文獻


1. Coresh J, BC. A, G. GT, L. A. Prevalence of chronic kidney disease and decreased kidney function in the adult US population: Third National Health and Nutrition Examination Survey. Am J Kidney Dis, 2003, pp 1-12.
2. WW. B, RM. P, SE. O, WF. K, A. C, SC. C, et al. Early detection of kidney disease in community settings: the Kidney Early Evaluation Program (KEEP). Am J Kidney Dis 2003; 2003.
3. Warnock DG, McClellan W, McClure LA, Newsome B, Campbell RC, Audhya P, et al. Prevalence of chronic kidney disease and anemia among participants in the Reasons for Geographic and Racial Differences in Stroke (REGARDS) Cohort Study:baseline results. Kidney Int 2005; 68: 1427-1431.
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5. Kopple JD. Nutritional therapy in kidney failure. Nutr Rev 1981; 39: 193-206.

被引用紀錄


林郁茹(2014)。個別化營養諮詢對後期慢性腎臟疾病患者營養狀況之探討〔碩士論文,臺北醫學大學〕。華藝線上圖書館。https://doi.org/10.6831/TMU.2014.00056

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