第二代抗精神病藥物引起之血糖調控的影響

在過去國內外許多文獻都提出服用第二代抗精神病藥物容易導致有代謝症候群的症狀。本篇收集了中部行政院衛生署草屯療養院中的113位患者分成四組對照組（n=73）、營養組（n=10）、藥物組（n=4）、合併組（n=26）在第0週及第24週各記錄一次生化血液值進行分析，所有被納入的患者平均住院時日有5.94年，探討利用飲食或藥物或兩者合併使用來控制空腹血糖值，對病患空腹血糖的改善成效，及所有生化檢驗值實驗前後的相比較。實驗結果發現，給予糖尿病餐食及給予餐食與降血糖藥物兩者共同給予，皆可有意義的下降空腹血糖，給予藥物及營養餐可讓HbA1c趨近正常標準，建議在往後治療病人方針上，可將飲食設為考慮的重點，若患者可透過飲食即可改善血糖，將可免去吃藥的痛苦，進而提高病患的生活品質。

關鍵字

抗精神分裂症藥物；糖尿病；糖尿病飲食

並列摘要

In past many researches have been reported take the second generation psychotic is prevalence metabolic. The purpose of the survey of nutrition or medicine or two of combine for these patients’ fasting blood glucose effect. We recruited psychiatric center department of health R.O.C. one hundred thirteen patients to divide into four parts control teams (n=73), nutrition team (n=10), drug team (n=4), combine team (n=26). In the 0 week and twenty-four weeks recorded patients’ fasting blood glucose to analysis. All the patients who live in the hospital average 5.94 years. Will explored either diet or medicine or both to control fasting glucose and improvement of patients’ fasting glucose. By biochemistry examination value experiment. We found that giving diabetes meal and diabetes diet combine oral hypoglycemic agents are worthy decrease fasting glucose. Moreover giving medicine and nutrition diet can make HbA1c tend to the average, when we suggest that diet should be take into consideration. If patients can improve blood glucose by dietary, they can avoid the inconvenient of taking medicine to raise patients’ the quality of life.

並列關鍵字

antipsychotic ； diabetes ； diabetes meal

參考文獻

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第二代抗精神病藥物引起之血糖調控的影響

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