急性腎盂腎炎是一種常見的泌尿系統疾病,可引起不可逆性腎功能損害--腎疤痕形成,並導致一系列併發症,如高血壓、慢性腎功能衰竭等。若對其進行早期診斷和積極治療,可避免上述異常的出現。核醫腎皮質切片是一種良好的顯影方法,它可用於急性腎盂腎炎的早期診斷和療效評價。本文以切片影像為基礎,提出一個評估急性腎盂腎炎的方法,其中包括三個步驟:(1)首先建立正常的腎功能樣本,(2)接著利用互資訊選出與病人最像的樣本並加以定位,(3)最後將病人及樣本加以分割成數個子影像做分析,並計算其缺損的體積及所喪失功能百分比。 量化急性腎盂腎炎對醫生的診斷有相當大的幫助,本文對此提出的方法不僅快速有效,且深具臨床實用價值。
Acute Pyelonephritis is a common disease of urinary system. It may cause irreversible renal failure, forming rental scarring, and result in a series of syndrome such as hypertension, chronic renal failure…, etc. A series of syndrome can be prevented by means of diagnosis and cure in the early time of pathogenesis. Renal cortex slices is a good way to cure Acute Pyelonephritis. The thesis is on the basis of the image of slices and the way of evaluating Acute Pyelonephritis is presented. It consists of three processes: establishing normal samples of renal function, using mutual information to select the most similar sample and dividing them into several sib-images to analyze and calculate the loss of bulk and percentage. Quantification of Acute Pyelonephritis is helpful for doctors in diagnosis. This thesis is not only effective but also qualified the practical of clinical value.