台灣氣喘病人抗氣喘用藥之研究

目的: 本研究在於探討台灣氣喘病患之抗氣喘藥物之使用材料與方法: 本研究是使用中央健保局之電腦化處方檔案，所分析之處方藥物依據解剖治療化學分類系統(Anatomical Therapeutic Chemical Classification System)分類，主要分析抗氣喘用藥之處方模式及用量。結果: 本研究共分析2,258,374張處方與930,652位病患，處方藥物以口服製劑為主，僅有4.94%與7.98%之氣喘病患分別接受吸入式類固醇及吸入式短效beta-agonists之治療。 45歲以下之氣喘病患被處方以口服短效beta-agonists之頻率最高，而45歲或以上之氣喘病患則最常以茶鹼治療。11.6%之台灣氣喘病童接受ketotifen治療(11.6%) 結論: 台灣氣喘病患，不論任何年齡層吸入劑之使用均偏低，尤其是吸入式類固醇。台灣氣喘病患之管理，似乎尚未達到現今氣喘診療指引所述之目標。應該鼓勵臺灣之醫師給與氣喘病患較多之吸入式藥物，尤其是吸入式類固醇。

關鍵字

氣喘；用藥；兒科；老人

並列摘要

Purpose: To describe the use of anti-asthmatic medications in Taiwanese asthmatic patients. Materials and Methods: The study used computerized prescription databases from the National Health Insurance Program, Taiwan, ROC. Drugs were classified according to the Anatomical Therapeutic Chemical Classification System. We analyzed the patterns and extent of medication use for asthmatic patients. Results: A total of 2,258,374 prescriptions from 930,652 patients were analyzed. Oral medications were most often prescribed. Only 4.94% and 7.98% of patients were treated with inhaled corticosteroids and inhaled short-acting beta-agonists, respectively. Patients younger than 45 years were treated most frequently with oral short-acting beta-agonists; while patients equal or older than 45 years were treated most frequently with methylxanthines. 11.6% pediatric patients in Taiwan received ketotifen. Conclusions: Physicians in Taiwan do not prescribe as much inhaled anti-inflammatory agents for the treatment of asthma in the asthmatics as suggested in the international treatment guidelines.

並列關鍵字

asthma ； medication ； pediatric ； geriatric

參考文獻

Adams RJ, Fuhlbrigge A, Finkelstein JA, Lozano P, et al. Impact of inhaled anti-inflammatory therapy on hospitalization and emergency department visits for children with asthma. Pediatrics 2001;107: 706-711.

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