Bromoalkyne can react with aniline to produce α-ketoamide in the presence O2 under ultraviolet. In our case, we use microfluidic but not traditional batch. Through different concentration, flow rate, and UV wavelength to find the best condition to get the highest conversion of product. The reaction under microfluidic is automatic , and is faster than traditional batch. Finally, our goal is to be able to synthesize the required compounds in large quantities.