穩定雙極性疾患患者之認知功能、睡眠狀態以及生活品質研究

Cognition, Sleep and life quality in patients with euthymic bipolar disorder

王介暉(Chieh-Hui Wang)

指導教授 ： 張文正

長榮大學/健康科學學院/醫學研究所/碩士(2009年)

https://doi.org/10.6833/CJCU.2009.00146

摘要

無資料

關鍵字

雙極性疾患；認知功能；睡眠；生活品質

並列摘要

Objective: The purpose of this study was to evaluate the association among cognitive functioning, sleep condition and life quality in euthymic bipolar patients.

Methods: 24 subjects of drugs free euthymic bipolar disorder and 40 age- and gender-matched healthy controls were included. Pittsburgh Sleep Quality Inventory, the Chinese version of the World Health Organization Quality of Life (WHO-QOL), and a battery of cognitive testes were completed.

Results: Patients group showed significant impairment only in domains of visual memory, verbal memory, general memory, and delayed recall, comparative to other previous studies. Self-rated QoL resulted in lower satisfaction in physical, mental, and overall health. For sleep profile, the results displayed significant difference in sleep quality, sleep latency, sleep efficiency, using drugs for sleep and daytime dysfunction in euthymic bipolar patients group.

Conclusion: The study further confirmed that, after obviating the influence of maintenance psychotropic treatment, patients with euthymic bipolar disorder still displayed significant difference in cognitive function, QoL, and sleep condition. Since it had been proposed that cognitive distortion in perceiving sleep might be a core mechanism in maintaining sleep disturbance, our data led us to hypothesize that sleep misperception could induce higher levels of anxiety and the fear about poor sleep may contribute to higher rate of hypnotics usage and impose further impact on patients’ quality of life. Large sample-sized studies are needed to be done to further elucidate this complex relationship.

並列關鍵字

bipolar disorder；cognition；sleep；life quality

參考文獻

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