延伸式場效電晶體應用於多重離子感測元件之研究

Study on Multi Ion Sensor of Extended Gate Field Effect Transistor

郜一匡(I-Kone Kao)

指導教授 ： 熊慎幹

中原大學/工學院/醫學工程研究所/碩士(2003年)

https://doi.org/10.6840/cycu200300539

摘要

中文摘要

血液中鉀、鈉離子濃度直接反應了人體腎臟之情況，亦表示了各種疾病之症候。例如，血液之酸鹼度會影響心臟之鉀離子代謝，而有心臟方面疾病之危險。由此可看出人體血液中鉀、鈉等離子之濃度係人體健康之指標亦是臨床上之重要參數。
本論文係以二氧化錫/氧化銦鍚玻璃架構之延伸式閘極場效電晶體為基礎，製作鉀、鈉離子選擇電極，將離子選擇物結胺黴素(valinomycin)和雙甲基四氧環十二烷十二甲基丙酸{bis[(12-crown-4) methyl] dodecylmethyl malonate,B12C4}與聚尿酸甲脂類(polyurethane)和聚氯乙烯(PVC)二種高分子製成離子選擇電極。實驗結果為聚尿酸甲脂類(polyurethane)中之親水性雙亞克力芳香聚尿酸鉀酯(hydro-aliphatic urethane diacrylate,EB2001)膜可包埋valinomycin和B12C4以測量鉀、鈉離子濃度，選擇電壓可達40~50 mV/decade 之變化，並求出酸鹼、鉀、鈉電極之電壓干擾參數。

關鍵字

二氧化錫 ； 延伸式場效電晶體 ； 鈉離子選擇電極 ； 鉀離子選擇電極

並列摘要

Abstract

The concentrations of potassium and sodium ion in blood can response the condition of kidney. In addition, acidosis is an important factor in the setting of myocardial ischemia. The inhibition of potassium ion current was decreased during acidosis. Therefore, the concentrations of potassium and sodium ion are the index of health and an significant parameter in clinical diagnosis
In this study, the extended-gate field effect transistor (EGFET), with was the SnO2/ITO glass structure, was applied to fabricate the potassium and sodium ion selective electrodes. The valinomycin and Bis[(12-crown-4) methyl]dodecyl- methylmalonate(B12C4) with two kinds of polymer (polyurethane and PVC) based on the EGFET were used for potassium and sodium ion selective electrodes. The polyurethane (Hydro-aliphatic urethane diacrylate,EB2001) membrane can improve the valinomycin and B12C4 to detect the potassium and sodium ions and its selectivity was about 40~50 mV/decade. Then , the potentiometric selectivity coefficient of SnO2 potassium and sodium electrodes will be obtained.

並列關鍵字

Potassium ion selective electrode ； Extended-gate field effect transistor ； Sodium ion selective electrode. ； Tin oxide

參考文獻

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