苯基疊氮化合物與具拉電子基之烯類反應之研究

The study of phenyl azides reaction with electron-withdrawing group alkenes

樓家豪(chia-hao Lou)

指導教授 ： 楊嘉喜

中原大學/理學院/化學研究所/碩士(2011年)

https://doi.org/10.6840/cycu201100829

摘要

本研究是利用苯基疊氮化合物(如:苯甲基疊氮、氯苯基疊氮)與具拉電子基之烯類(例:甲基丙烯酸甲酯、丙烯腈)進行反應，前人因苯基疊氮化合物在高溫時有爆炸危險，所以皆不嘗試高溫實驗，吾人試以一百度進行反應，發現並無爆炸之虞，故探討其以高溫環境下之反應結果與前人所述的室溫下及常溫高壓下的結果有何相異之處。
本實驗特色在於能快速並簡單的製備氮丙啶，先以苯胺作為原料，合成出苯基疊氮化合物，再將苯基疊氮化合物與具拉電子基之烯類進行反應，實驗中大多並不需要使用溶劑只要在攝氏一百度的條件下就可完成，生成氮丙啶與三唑化合物，其中三唑化合物會隨著溫度的增加而加速變化成氮丙啶。

關鍵字

苯基疊氮化合物 ； 具拉電子基之烯類

並列摘要

This study is the use of phenyl azide (for example: benzyl azide, chlorophenyl azide) with the electron-withdrawing alkenes (for example: methyl methacrylate, acrylonitrile) reaction.

To investigate the reaction under high temperature condition between the previous results at room temperature and under high pressure at room temperature compared the results of what these differences.

The experiment features a fast and simple preparation aziridine, let aniline turn into azidobenzene,and then reaction with the electron-withdrawing alkenes under 100 degree. The products are aziridine and triazole . the triazole turn into aziridine as faster as temperature increase. most patients do not need to experiment in the use of solvents as long as under high temperature conditions can be completed.

並列關鍵字

electron-withdrawing group alkenes ； phenyl azide

參考文獻

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