水溶性歧狀高分子奈米粒子合成之研究

Diethylene glycol ether as triply branched dendritic anchors to CdSe/ZnS core/shell type nanoparticles: potential hydrophilic fluorescent probes

巴瓦(VIJAY DATTARAM PAWAR)

指導教授 ： 陳建添

國立臺灣師範大學/理學院/化學系/博士(2005年)

摘要

合成以CdSe/ZnS核之歧狀高分子連結之奈米粒子及其應用.
氧鉬金屬催化醇類磷酯化反應.
掌性氧釩錯合物在二級醇磷酯化合物之不對稱氧化.

關鍵字

不對稱催化

並列摘要

Abstract
Chapter I. Diethylene glycol ether as triply branched dendritic anchors to CdSe/ZnS core/shell type nanoparticles: potential hydrophilic fluorescent probes
During past decade synthesis of water soluble nanoparticles has been attracted many chemists, due to its wide range of applications especially in the labeling of biomolecules. For the study of nanohybrids in biology, robust water soluble nanoparticles required. Several research groups dedicated their efforts to make water soluble CdSe-ZnS core/shell nanoparticles. In this chapter we reported a novel method towards synthesis of nanoparticles by wrapping triply branched dendritic dietylene glycol substituted galaimde. We also successfully demonstrated new biphasic systems for ligand exchange process. The resulted nanohybrids were highly water soluble and make its three free sites for further functional group modification and useful tool for minimizing multivalent interaction in carbohydrate and proteins.
Chapter II. Efficient Synthesis of Organophosphorus compounds by Oxometallic catalysts
In this chapter we studied synthesis of different kind’s organophosphorus compound in two sections. In section 1 from this chapter we have documented a novel method for Phosphorylation of alcohols using amphoteric and water tolerant MoOCl4 catalyst. The method reported herein is compatible with all kind of functionalities as well as acid labile acetonide, THP ether and TBS ethers. This method can be used for phosphorylation of primary, secondary and tertiary alcohols in high isolated yields. In Section 2 we have illustrated highly enantioselctive synthesis of α-hydroxy phosphonates via aerobic oxidation of racemic hydroxy phosphonates using chiral vanady(V) complexes. Along with this we also discussed the catalytic version Pudovik reaction using MoO2Cl2 catalyst. The kinetic resolution process gave 99% enantiomerically pure compounds with 50% isolated yield.

並列關鍵字

Nanoparticles ； Phosphorylation ； Aerobic oxidation