- 學位論文
Organocatalytic domino double Michael and the subsequent radical cyclization or Pictet-Spengler reaction
Organocatalytic domino double Michael and the subsequent radical cyclization or Pictet-Spengler reaction
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摘要
利用共軛酯類與α、β-不飽和醛類藉由不對稱有機催化試劑進行double-Micahel 反應建構出多取代之六員環衍生物，再藉由自由基環化反應或Pictet-Spengler反應建構出具有吲哚的化合物，而且具有高鏡像選擇性，也利用X-ray單晶繞射分析決定出其絕對立體組態。
關鍵字
有機催化並列摘要
Asymmetric synthesis of highly functionalized compounds were achieved by a sequential organocatalyzed double Michael reaction of conjugated esters and α,β - unsaturated aldehydes, and radical cyclization or Pictet-Spengler reaction with high enantioselectivities and modrate diastereoselectivities. The absolute stereochemistry of major diastereomer was determined by X-ray analysis.
並列關鍵字
organocatalytic參考文獻
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被引用紀錄
林政緯（2015）。1. Synthesis of Highly Functionalized Decalines Using Photoredox Catalyst and Organocatalyst
2. Transformation of Nitroalkanes to Nitrones Using Phtoredox Catalysis〔博士論文，國立中正大學〕。華藝線上圖書館。https://www.airitilibrary.com/Article/Detail?DocID=U0033-2110201614033922