In this study, CFD Method is applied to study the flow characteristic of a BiVACOR Artificial Heart. The incompressible flow COUPLE scheme with realizable k-ε turbulence model is using to investigate the impeller of the artificial heart at different speeds and with different inlet flow rate. The test parameters are the three sets of an inlet flow, and 5 sets pump speed. The results found the suspended impeller with high rpm and low inlet flow can produce higher pressure differential. On the other hand, the suspended impeller with low rpm and high inlet flow results contrary. Moreover, the match by the pump rpm and inlet flow also affect the high shear stress distribution.