磁控濺射多元化合物鍍層在不銹鋼表面抗菌的研究

Investigation of Surface Disinfection of Magnetron Sputtered Multiphase on Stainless Steel

聶少三(Shao-Shan Nieh)

指導教授 ： 言午垤綦

大同大學/工程學院/生物工程學系所/碩士(2004年)

摘要

中文摘要

磁控濺射鍍膜技術可以在金屬表面形成各種結構層次不同的薄膜。濺射鍍膜法可以有釵h創新的應用，尤其是一種被稱為多元化合物的鍍層。最近這幾年以來，物理氣象沉積法(PVD)對材料進行表面改質在工業已廣泛被運用；例如抗侵蝕性航太元件、耐磨耗硬質陶瓷持薄膜、以及嶄新運用在生物檢測與特異化學性質的鍍層。然而，真空鍍膜技術應用在抑制細菌成長的效能兩者之間很難被聯想在一起。在現代人類的生活中，不銹鋼製品已經廣泛的被使用。基於這個動機，假使對不銹鋼產品進行表面改質，不但在實質上提升產品價值同時也擴大了其應用範圍。例如降低由醫院或是公共場所的細菌感染。
為了證實抗菌鍍膜在不銹鋼試片上的抑菌效力，將試片分成三組，Group A上面沒有鍍層，Group B為氮化鈦鍍層，Group C為多元化合物鍍層。本研究的結果顯示，Group A與Group B表面抗菌率並沒有顯著差異，在Group C表面的多元化合物鍍層對金黃葡萄球菌之抑菌效果達99%以上，顯示(Ti-Ag)N複層鍍膜可以有效抑制金黃葡萄球菌在金屬表面生長與繁殖。進一步地說，在基材表面披覆多元化合物鍍層，與一般單相TiN鍍層或者基材表面沒有鍍層相比，多元化合物鍍層具有優越的抗菌性。本研究最主要的焦點是探討濺射鍍膜在不銹鋼表面披覆形成具有機能性結構鍍層，與其關於抑制微生物存活兩者之間的關聯性。

關鍵詞：抗菌性、磁控濺射鍍膜法、多元化合物鍍層、金黃色葡萄球菌。

關鍵字

抗菌性、磁控濺射鍍膜法、多元化合物鍍層、金黃色葡萄球菌。

並列摘要

Abstract

Magnetron sputtering deposition (MSD) technologies allow the production of various structures of thin films on most metal surfaces. This permits many new applications, especially for so-called multiphase. In recent years, physical vapour deposition (PVD) was widely used in industries such as corrosion resistant coatings for aerospace, hard ceramic coatings for wear resistance, and coatings with novel biosensors and distinct from chemical properties. However the associated disinfection ability was poorly understood. Stainless steel has been extensively used in modern human life. For this reason, if surface modification technologies are used, it not only substantially increases the value of stainless steel but also expend scope of applications, such as to reduce a hospital or contact with public place acquired infection.
In order to find out the efficacy factors of antimicrobial coatings in the samples, the samples were divided into three groups: uncoated (Group A), TiN coatings (Group B) and the multiphase (Group C). In this study, Group A and Group B have no significant difference in antimicrobial rate. Group C having the results for coatings test shows the rate of Staphylococcus aureus reduction is more than 99%. It revealed that hybrid coatings (Ti-Ag) N can effectively inhibit the bacterial growth on stainless steel. In other words, multiphase leads to a better superior layer antimicrobial than TiN with a non-reactive surface modification. The particular aim of this study was focused on some relevant correlations between the surface of sputtering coated on stainless steel and the disinfection ability of this surface in air.

Keywords: Disinfection, Magnetron sputtering deposition, Multiphase,
Staphylococcus aureus.

並列關鍵字

Disinfection ； Magnetron sputtering deposition ； Multiphase ； Staphylococcus aureus.

參考文獻

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