利用壓克力假體和EBT膠片比較不同材質腔內固定器使用在舌癌放射線治療病人的劑量分布

在舌癌的放射治療中會使用腔內固定器(intro-oral block)將舌頭固定並且提高舌頭表面的劑量。但不同材質的固定器會造成不同的劑量分佈，所以在本實驗中使用四種不同材質之腔內固定器，分別在左右對照（Bilateral beam）治療計畫、四照野（4 fields）治療計畫以及強度調空放射治療（Intensity Modulation Radiation Therapy，IMRT）治療計畫等三個治療計畫中使用不同材質之腔內固定器測量其單次治療之劑量分布。本實驗主要的測量工具為EBT 底片，將照射過的EBT 底片使用軟體FILMQA做分析得到結果。結果顯示當在舌癌的放射治療中時使用高密度的腔內固定器不僅可以提高舌頭表面的劑量也可以降低周圍組織所接受的劑量。

關鍵字

EBT膠片； FILMQA ；腔內固定器；口腔癌

並列摘要

Radiation therapy in the tongue cancer patient by using intro-oral block will use to fix the tongue and raise the tongue surface dose. However, the intro-oral block of different materials will cause different dose distribution, so in this experiment we using four different materials to fix the tongue .The intro-oral blocks will be used in three different treatment plans respectively, the Bilateral beam treatment plan, 4 fields treatment planning and Intensity Modulation Radiation Therapy ( IMRT) treatment planning. Finally, we measure the dose distribution with four different materials of intro-oral blocks. In this study, we use the EBT film to measure the dose, and also use the FILMQA to do the analysis of the EBT film. The results show that when we use high-density intro-oral block to treat the tongue cancer patient, it will not only increase the surface dose of the tongue may also reduce the dose to the nearby normal tissues.

並列關鍵字

EBT film ； FILMQA ； Tongue cancer ； Intro-oral block

參考文獻

[1] Ji-An Liang, An-Cheng Shiau, Ching-Hsiung Su, Wen-Pin Shih, Jia-Ying Pan, Dose verification for intensity modulated radiation therapy, Therapeut Radiol. Onco1., 12(3), p227-233, 2005.

[4] R. Mayer, A. Williams, T. Frankel, Y. Cong, S. Simons, N. Yang, R.Timmerman, "Two-dimensional film dosimetry application inheterogeneous materials exposed to megavoltage photon beams," Med.Phys. vol.24. p455-60. 1997.

[5] Jacqueline Esthappan, Sasa Mutic, William B. Harms, James F. Dempsey, Daniel A. Low, Dosimetry of therapeutic photo beams using an extendeddose range film, Med. Phys., Vol. 29(10), p2438-2445, 2002.

[6] Stanislav M. Vatnitsky, Radiochromic film Dosimetry for clinical proton beams, Appl. Radiat. Isot., vol. 48, No. 5, pp643-651, 1997

[7] A. Piermattei, R. Miceli, L. Azario, A. Fidanzio, and S. delle Canne,Radiochromic film dosimetry of a low energy proton beam, Med. Phys. 27(7), p1655-1660, July 2000

延伸閱讀

蔡維達、李哲暐、傅筱如（2016）。弧形強度調控放射治療低分次治療肺癌病人皮膚劑量之假體研究。中華放射線技術學雜誌，40(4)，219-226。https://www.airitilibrary.com/Article/Detail?DocID=16849418-201612-201701090004-201701090004-219-226
陳韋霖、梁雲、張寶樹、劉明祥、張瑛真（2019）。比較有無整平濾片射束之周邊低劑量於立體定位消融性放射治療和於旋弧調控放射治療。南臺灣醫學雜誌，15(1)，35-47。https://doi.org/10.6726/MJST.201906_15(1).0004
Su, J. P., Jaw, T. S., Chen, C. Y., Kuo, Y. T., Hsieh, T. J., Lee, S. H., & Lin, C. C. (2010). 自動管電流調整與固定管電流多排層偵檢器電腦斷層肝臟攝影：影像品質及輻射劑量之比較. 中華放射線醫學雜誌, 35(3), 131-142. https://www.airitilibrary.com/Article/Detail?DocID=10188940-201009-201101130027-201101130027-131-142
林怡君（2006）。應用蒙地卡羅方法模擬放射手術之小照野劑量分佈〔碩士論文，國立清華大學〕。華藝線上圖書館。https://doi.org/10.6843/NTHU.2006.00332
Chiu, S. F., Gou, S. B., Shen, K. H., & Chiang, W. F. (2018). Application of a Fluorescence Visualization Loss System to Delimit the Resection Margin of Oral Cancer and Oral Precancer- A Serial Cases Report. 臺灣口腔顎面外科學會雜誌, 29(2), 96-104. https://www.airitilibrary.com/Article/Detail?DocID=a0000494-201806-201807310018-201807310018-96-104

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利用壓克力假體和EBT膠片比較不同材質腔內固定器使用在舌癌放射線治療病人的劑量分布

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