口腔內疣狀黃瘤：七個病例報告

Oral Verruciform Xanthoma: Report of Seven Cases

張松文(Sung-Wen Chang) ； 林正仲(Cheng-Chung Lin) ； 陳中和(Chung-Ho Chen)

《中華民國口腔顎面外科學會雜誌》 11卷1期 (2000/03) Pp. 18-25

https://doi.org/10.7104/CJOMS.200003.0018

摘要

疣狀黃瘤(verruciform xanthoma) 是口腔內相少見的良性腫瘤。自1971年Shafer提出報告以來，至今大約220個病例發表，其中約80%發生在口腔黏膜，其餘發生在生殖器黏膜或是皮膚上。口腔內最常發生的為牙齦及齒槽黏膜，其他如舌側緣、頰黏膜、口底亦有可能，嘴唇較罕見。此病灶生長緩慢，無明顯症狀。本文提出七個病例報告，年齡分佈17~52歲，男女比為6:1，發生位置涵蓋口腔各部位，包括牙齦、硬?、舌頭、前庭區黏膜等。七個病患皆接受保守性切除，其中五例平均13年以上追蹤，一例9個月，另一例1個月的追蹤，術後情況良好皆無復發情形。此病變的臨床上最常被診斷為乳頭狀瘤，其次為乳頭狀增生、白斑症、或是疣狀上皮細胞癌。臨床醫師應特別注意其被誤診為惡性病灶的風險，以免造成不適當的過度治療。

關鍵字

疣狀黃瘤 ； 口腔 ； 泡沬細胞

並列摘要

Verruciform xanthoma is a very rare benign lesion of the oral cavity. Since Shafer’s 1971 paper, there have been 220 cases reported in the literature, of which 80% occurred in the oral mucosa. The remainder occurred either in mucosa of the urogenital system or on the skin. This lesion grows slowly and shows no obvious symptoms. The present study will discuss seven cases of oral verruciform xanthoma. There were six males and one female. The age ranaged from 17 to 52 years. The lesions occurred in the gingival, hard palate, vestibular mucosa, and tongue. All seven cases underwent conservative excision of the lesions. In clinical practice, it is most commonly diagnosed as papilloma, papillary hyperplasia, leuko-plakia, or verrucous carcinoma. Clinical physicians should pay particular attention to the risk of misdiagnosing this condition as a malignant tumor, in order to avoid overtreatment.

並列關鍵字

verruciform xanthoma ； foam cell