高良薑萃取物抗氧化與PC12細胞生長作用

Antioxidant Activity and Effect on PC12 Cell Growth of Alpinia Officinarum Extracts

陳華鑫(Hua-Sin Chen) ； 張嘉麟(Chia-Lin Chang) ； 林博楷(Po-Kai Lin) ； 王建旻(Chien-Ming Wang) ； 賴家宏(Guia-Hung Lai) ； 林哲三(Che-San Lin)

《傳統醫學雜誌》 23卷1期 (2012/10) Pp. 1-10

https://doi.org/10.30038/JTM.201210.0001

摘要

高良薑主要用於胃和十二指腸潰瘍病、慢性胃炎及胃部疼痛，近年來文獻報導高良薑具備不同的生理活性，如抗微生物、抗肝癌與抗氧化等，本硏究主要是探討高良薑萃取物清除l,l-diphenyl-2-picrylhydrazyl （DPPH）自由基的能力及對PC12細胞生長的影響，結果得知高良薑95%乙醇萃取物清除DPPH自由基的能力最佳，而且促進PC12細胞生長的效果最好，高良薑具有在食品與醫藥上應用於預防或治療神經退化性疾病開發的潛力。

關鍵字

高良薑萃取物 ； 自由基 ； PC12細胞生長

並列摘要

Alpinia officinarum is primarily applied to stomach and duodenal ulcer diseases, chronic gastritis, and stomach pain. Recent literature has reported that A. officinarum possesses various physiological activities such as anti-microbes, anti-hepatomas, and anti-oxidants. In the research, we discuss the ability of A. officinarum extracts removing 1, 1 -diphenyl-2-picrylhydrazyl (DPPH) free radicals and the effects of A. officinarum extracts on PC12 cell growth. The results show that the 95% ethanol extract of the A. officinarum had the best scavenging capacity of the DPPH free radicals. The effect of facilitating PC12 cell growth was optimum. A. officinarum possesses the application and exploitation for prevention or treatment of neurodegenerative diseases in the food and medicine.

並列關鍵字

Alpinia officinarum Extracts ； Free Radicals ； PC12 Cell Growth