Internal jugular vein thrombosis is a rare and life-threatening disorder. Before antibi-otics, deep neck infection was the major etiogical factor, as opposed to direct trauma to the internal jugular vein either from iatrogenic catheterization or repeat injection by drug abusers, A thrombosed internal jugular vein is an important differential diagnosis in the assessment of a lateral neck mass. A 34-year-old woman presented to our out patient department with a three week history of a painful left sided neck mass, Initially, she had noticed a sore throat and neck pain with assocated headache and dizziness. Despite having some medication prescribed at a clinic, her symptoms persisted and the mass became larger, at which point she presented to the hospital for further management. After physical examination, fine needle aspiration and imaging, a left internal juglar vein thrombosis was strongly suspected. As the thrombus was well organized and given concerned of potentially lethal complications, surgical extirpation was performed. Opera-tive findings revealed marked adhesion between the internal jugular vein and surrounding tissues. The vein itself was markedly dilated and filled with intraluinal thrombus from the level of the subclan vein to just above the omotyoid muscle,Care was taken to identify and preserve the thoracic duct to prevent leakage or fistula formation. The hospital admission was uneventful, the patient was discharged sumptom free. We believe that the incidence of internal jugular vein thrombosis is underestimated, as it may be ignored in the context of overwhelming underlying systemic disease or hypercoagula-bility secondary to various causes. The diagnosis should always be considered when assessing a lateral neck mass.