Cefpodoxime對於耳鼻喉感染症之臨床試驗

Clinical Trial of Cefpodoxime in ENT Infections

黃啟仲(Chi-Chung Huang) ； 張燕良(Yen-Liang Chang) ； 鍾易晉(Yih-Jinn Jong) ； 李憲彥(Shiann-Yann Lee)

《中華民國耳鼻喉科醫學會雜誌》 29卷2期 (1994/04) Pp. 101-106

https://doi.org/10.6286/1994.29.2.101

摘要

Cefpodoxime乃屬於第3代頭孢子鰴素類之抗生素藥物，其特點在於口服吸收率較高，而血中半衰期較長，與以術頭孢子鰴素類藥物相比，在有效性及方便性上均有改進。試驗結果顯示使用本藥對於耳鼻喉科門診常見之感染症，可達84%的細菌消失率及80%的臨床症狀改善率，顯示對耳鼻喉科門診常見的感染症可有良好的控制。至於副作用方面，只有2例患者有上腹不適感，停藥後隨即消失。Cefpodoxime對耳鼻喉科醫師在治療患者時，又多一種有效而安全的利器。

關鍵字

頭孢子鰴素 ； 耳鼻喉感染症

並列摘要

Bacterial infection is one of the most common and important problem in the ENT fields. Antibiotics are often necessary for the treatment and prevention of bacte-rial infections. Cefpodoxime is a new kind of the 3rd generation cephalosporin. In our trial, the efficacy of cefpodoxime was monitored for its bactericidal effect and clinical improvement. The results showed 84% bacteriological and 80% clinical improvement. No biochemical or hematology-ical deturbance was found in our patients. Regarding efficacy, convenience and safety, we suggest that cefpodoxime is a new choice for the treatment of bacterial infec-tions in the ENT fields.

並列關鍵字

cephalosporin ； ENT infections