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摘要


灼傷瘢痕引起腫瘤很少見,最常見是鱗狀細胞癌而基底細胞癌非常少,大都發生於未植皮的灼傷部位。一般基底細胞癌發生於較淺之灼傷瘢痕,其汗腺及毛囊未完全破壞,而鱗狀細胞癌則多發生於較深灼傷瘢痕,灼傷至腫瘤發生的時間即遲滯期與灼傷時的年齡成反比,其愈年輕的時候灼傷,遲滯期愈長而基底細胞癌的遲滯期比鱗狀細胞癌較短。 本院一位58歲男性病人,5年前因電燈泡接觸性灼傷於右背部,且於瘢痕中央有一表淺的慢性潰瘍傷口,經病理證實為淺性基底細胞癌,其原因可能是表淺性的灼傷其毛囊及汗腺未完全破壞。

並列摘要


Burn scar carcinomas occur at any age and have no race predilection. They are found predominantly in adults and occurs more commonly in males with male to female ratio about 3:1. Burn scar carcinomas develope primarily on the extremities espcially on the flexion area and head neck region, but rarely in the trunk which took only approximately 10% of burn scar carcinoma. Carcinomas arising in burn scar are rare. The most common type is malignant burn degeneration result in squamous cell carcinoma. Much rarer is malignant degeneration into basal cell carcinoma. The majority of burn scar carcinomas occurs in burns that remain ungrafted. The basal cell carcinomas develope in the more superficial burn scars where the hair follicles and sweat glands have not been destroyed whereas the squamous cell carcinoma arise in deep ulcerating lesions as associated with extensive scar. The lag period prior to induction of malignancy is inversely proportional to patient's age at the time of burn. The lag period for burn scar basal cell carcinoma generally shorter than that for squamous cell carcinoma. Recently a case of burn scar basal cell carcinoma was seen by contacting an electric lamp in our hospital. A 58 years old man sustained a burn injury on his back 5 years ago. There is a superficial ulcer in the middle of the burn scar which pathologically proved to be superficial basal cell carcinoma. It is postulated that the injury of the superficial hair follicles and sweat glands could be the cause of the burn scar basal cell carcinoma.

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