Canine Hyperadrenocorticism: A Retrospective Study of 59 Cases During 1995 to 2000

犬腎上腺皮質功能亢進症：1995－2000年間59病例之回溯性研究

黃慧璧(Hui-Pi Huang) ； 連于欣(Yu-Hsin Lien) ； 連澤仁(Tse-Jen Lien)

《中華民國獸醫學會雜誌》 27卷4期 (2001/12) Pp. 232-238

https://doi.org/10.7009/JTCSVS.200112.0232

摘要

針對1995-2000年間前來國立台灣大學附設動物醫院小動物皮膚與代謝性疾病特約門診中的59隻罹患腎上腺皮質功能亢進症犬隻進行研究。1995-2000年間犬腎上腺皮質功能亢進症的罹患率為0.6%（總病例）至2.9%（初診病例）。59隻犬包括16隻混種犬、10隻Maltese Terrier、8隻Miniature Poodle、7隻Pomeranian、4隻short-haired Dachshund、4隻Miniature Pinscher、3隻Cocker Spaniel、2隻Pekinese、與Chihuahua、Miniature Schnauzer、Shetland Collie、Shih-Tzu、Yorkshire Terrier各一隻。平均年齡為9.9±2.8歲，其中有24隻母犬、8隻已絕育母犬、25隻公犬、2隻已絕育公犬。主要的臨床呈象包括嗜食(98.3%)、多尿(96.6%)、頻渴(93.2%)、pot-belly (88.1%)、皮毛病變(84.4%)、心肺循環系統的障礙(79.7%)與精神不振(55.9%)。Alkaline phosphatase升高(89.8%)、高膽固醇血症(71.2%)、alanine aaminotransferase升高(55.9%)、高血糖症(32.2%)、蛋白尿(67.8%)與潛血尿(35.6%)是常見的檢驗異常。在此59病例中，56例(89.8%)為腦下垂體型，6例(10.2%)為腎上腺腫瘤。近80%病例同時出現心肺循環系統的障礙，10例(16.9%)併發糖尿病。

關鍵字

腎上腺皮質功能亢進症 ； 犬 ； 罹患率 ； 臨床呈象 ； 血液檢驗結果

並列摘要

Fifty-nine dogs with hyperadrenocorticism were studied, All cases were admitted to the Specialized Clinics for Dermatology and Metabolic Disorders in the National Taiwan University Veterinary during 1995 to 2000, The overall prevalence of hyperadrenocorticism during 1995 to 2000 was estimated between 0.6% (both first and second opinion cases) and 2.9% (first-opinion cases). Breeds in this study included 16 mongrels, 10 Maltese Terriers, 8 Miniature Poodle, 7 Pomeranians, 4 each of short-haired Dachshunds and Miniature Pinschers, 3 Cocker Spaniels, 2 Pekineses, 1 each of Chihuahua, Miniature Schnauzer, Shetland Collie, Shih-Tzu and Yorkshire Terrier. The mean age of this group was 9.9±2.8 years. There were 24 intact females, 8 neutered females, 25 intact males and 2 neutered males. The most common clinical signs were polyphagia (98.3%), polyuria (96.6%), polydipsia (93.2%), pot-belly (88.1%), cutaneous abnormalities (84.4%), signs related to compromised cardiopulmonary function (79.7%), and lethargy (55.9%). The most predominant laboratory abnormalities included elevated alkaline phosphatase (89.8%), hypercholesterolemia (71.2%), elevated alanine transferase (55.9%), hyperglycemia (32.2%), proteinuria (67.8%) and occult hematuria (35.6%). Among these 59 cases, 53 were pituitary-dependent (89.8%), 6 had adrenal tumors (10.2%). Near 80% of the cases was presented with certain degree of cardiopulmonary problems. Ten cases had concurrent diabetes mellitus (16.9%).

並列關鍵字

Hyperadrenocorticism ； Dog ； Prevalence ； Clinical signs ； Laboratory findings