Enhanced Sentinel Lymphoscintigraphic Mapping in Breast Tumor

層次遮蔽技術應用於乳房腫瘤前哨淋巴偵測造影改進

陳毓雯(Yu-Wen Chen) ； 賴永昌(Yung-Chang Lai) ； 徐健欽(Chien-Chin Hsu) ； 侯明鋒(Ming-Feng Hou)

《The Kaohsiung Journal of Medical Sciences》 19卷7期 (2003/07) Pp. 339-344

摘要

The graded shield technique was developed to increase the sentinel node detection rate by improving lymphoscintigraphic image contrast. In a 6-month period, 50 women with clinical suspicion of early stage breast cancer (Tl and 12 tumors) were enrolled in this study. The patients had a mean age of 47.2±10.3 years. A composite graded shield was constructed using three concentric layers of leaded plastic measuring 3 cm, 5 cm, and 7 cm each in diameter. The graded shield was designed with a movable Velcro backing for accurate positioning over the injection site. Images were acquired with a vertical angle dual-head gamma camera using an established injection procedure developed at our institution. The rate of detection of sentinel lymph nodes using lymphoscintigraphic mapping improved from 74% (37/50 patients) to 96% (48/50) using the graded shield (p ＜ 0.05). In addition to the increased detection rate, our technique also increased the number of nodes detected and improved visualization of the adjacent lymphatic basin. By enhancing nodal contrast, we have demonstrated that the graded shield technique is an effective method for improving the rate of sentinel node detection.

關鍵字

前哨淋巴結 ； 乳癌 ； 層次遮蔽技術

並列摘要

The graded shield technique was developed to increase the sentinel node detection rate by improving lymphoscintigraphic image contrast. In a 6-month period, 50 women with clinical suspicion of early stage breast cancer (Tl and 12 tumors) were enrolled in this study. The patients had a mean age of 47.2±10.3 years. A composite graded shield was constructed using three concentric layers of leaded plastic measuring 3 cm, 5 cm, and 7 cm each in diameter. The graded shield was designed with a movable Velcro backing for accurate positioning over the injection site. Images were acquired with a vertical angle dual-head gamma camera using an established injection procedure developed at our institution. The rate of detection of sentinel lymph nodes using lymphoscintigraphic mapping improved from 74% (37/50 patients) to 96% (48/50) using the graded shield (p ＜ 0.05). In addition to the increased detection rate, our technique also increased the number of nodes detected and improved visualization of the adjacent lymphatic basin. By enhancing nodal contrast, we have demonstrated that the graded shield technique is an effective method for improving the rate of sentinel node detection.

並列關鍵字

sentinel lymph node ； breast cancer ； graded shield