Effect of green tea consumption on human brain function in resting-state functional MRI

Hui Wang ； Wei Sun ； Yan Chang ； Zhenzhou Wu ； Yajie Xu ； Erlei Wang ； Lei Wang ； Peiwei Yi

《Asia Pacific Journal of Clinical Nutrition》 28卷4期 (2019/12) Pp. 740-746

https://doi.org/10.6133/apjcn.201912_28(4).0010

摘要

Background and Objectives: Green tea is reported to have wide benefits on psychological states and cognitive functions. Studies that focus on the underlying neural mechanisms of green tea are limited to its single composition while people usually benefit from green tea water that contains various composition. In this study, we examined the human brain activity changes after drinking natural green tea by using regional homogeneity and functional connectivity based on the resting-state functional MRI technique. Methods and Study Design: Fifteen healthy volunteers participated in two imaging sessions: a control (water) session and a green tea session, each session comprised a predrinking, drinking, and postdrinking section, during the drinking section, the subject consumed 200 mL of green tea infusion or water in 3 to 5 minutes. Then the post-tea and post-water imaging data were selected for regional homogeneity and functional connectivity analysis. Results: Our results revealed that, compared with the control group, the green tea group exhibited an increased regional homogeneity in the frontal, parietal, and occipital areas of the brain, decreased regional homogeneity values in the left cuneus and left lingual gyrus, mainly a decreased functional connectivity in the default mode network, somatosensory, visual cortex, and parieto-frontal areas and enhanced functional connectivity in brain regions associated with memory. Conclusions: This result indicates that green tea consumption impacts the brain activity during resting state.

關鍵字

green tea ； resting-state functional MRI ； functional connectivity ； brain function ； default mode network