Water quality monitoring is nowadays an essential environment issue. Compared to the traditional survey, using remote sensing data to estimate the water quality in the reservoir is more time-saving, efficient in a large area. This study utilized the satellite images of FormoSat-5 (FS5), Landsat 8 (L8), and geographic information system (GIS) to monitor the water quality of Shimen and the Baoshan Reservoir. The predicted regression model was built based on the spectral data of the collected satellite images and ground-referenced data of the water quality of the Shimen Reservoir and Baoshan Reservoir. The R2 of chlorophyll-a (ChIa), secchi disk depth (SDD), chemical oxygen demand (COD), and total phosphorus (TP) in Shimen and Baoshan Reservoir are between 0.61 and 0.75. The mapping results can not only present the spatial distribution of water quality in the reservoir area, but also indicate that water quality has high correlation with the land use in the reservoir coastal area. In this study, the procedure of combining remote sensing data and the regression model to estimate the spatial distribution of water quality of the reservoir can be promoted to monitor the water quality of other reservoirs in Taiwan in the future.