- 期刊
Use of Radial Probe Endobronchial Ultrasound (EBUS) in Diagnosing Atypical Pulmonary Infection
摘要
Background: Bronchoscopy with radial probe endobronchial ultrasonography (EBUS) has been utilized to assess peripheral pulmonary lesions and to identify parenchymal lung lesions for biopsy. However, there is no information on the use of bronchoscopy with EBUS in the diagnosis of atypical pulmonary infection. Identifying the unknown pathogens responsible for atypical pulmonary infections remain a diagnostic challenge. Therefore, we investigated the usefulness of bronchoscopy with EBUS in the diagnosis and management of patients with atypical pulmonary infection. Methods: The diagnostic yields of EBUS from patients with atypical pulmonary infection treated in a tertiary university hospital between December 2007 and December 2010 were analyzed retrospectively. Results: A total of 78 patients with atypical pulmonary infection were enrolled in the study. The majority of those patients (n=57, 73%) also had underlying disease, such as diabetes mellitus (n=26) or malignancy (n=12). A total of 78 microorganisms were isolated or identified by histopathology, including Mycobacterium tuberculosis (n=59), Aspergillus (n=8), Cryptococcus (n=6), Pneumocystis jiroveci (n=3), and mucormycosis (n=2). The definitive diagnosis rate using EBUS was 82.1% (n=64), including 86.4% for Mycobacterium tuberculosis (51/59), 87.5% for Aspergillus (7/8), 100% for Pneumocystis jiroveci (3/3) and mucormycosis (2/2), and 16.7% for Cryptococcus (1/6). EBUS examination assisted in both the diagnosis (82.0%) and management (78.2%) of patients. Pneumothorax, which occurred in 2 patients (3%), was the only complication. Conclusion: Bronchoscopy with EBUS is a useful diagnostic tool for patients with atypical pneumonia. This technique can be particularly helpful in diagnosing patients without an identified pulmonary infection pathogen.
延伸閱讀
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