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有氧運動訓練對第二型糖尿病患胰島素抗阻性、血清脂質與心肺耐力之成效

Effects of Aerobic Exercise Training on Insulin Sensitivity, Serum Lipids, and Cardiorespiratory Fitness in Patients with Type 2 Diabetes

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摘要


Little is known about the relation of planned exercise to insulin sensitivity in type 2 diabetes in Taiwan. Thus, the purpose of this study was to explore the effects of a 12-week aerobic exercise program on insulin sensitivity, serum lipids, cardiorespiratory fitness, and blood pressure in patients with type 2 diabetes. This study had a quasi-experimental design and used purposive sampling. The samples consisted of 13 eligible patients with type 2 diabetes. Each subject underwent a 12-week exercise program (30 minutes a day, 3 days a week, and at 60% maximum oxygen uptake). Wilcoxon signed rank test was performed to examined pre- and post-training differences. At the end of the program, the results indicated that fasting blood glucose and fasting insulin were significantly decreased (p< 0.05); however, the HOMA-IR index, a valid estimate of insulin resistance, did not significantly change. Among serum lipids, total cholesterol, triglyceride and LDL also decreased significantly. Additionally, the cardiorespiratory fitness was elevated nearly 12.4% (p< 0.01). Furthermore, blood pressure was also improved (p< 0.01). It is concluded that exercise can improve insulin sensitivity, reduce serum lipids, increase cardiorespiratory fitness, and lower blood pressure in type 2 diabetes patients. ( J Rehab Med Assoc ROC 2003; 31(4): 207 - 215 )

並列摘要


Little is known about the relation of planned exercise to insulin sensitivity in type 2 diabetes in Taiwan. Thus, the purpose of this study was to explore the effects of a 12-week aerobic exercise program on insulin sensitivity, serum lipids, cardiorespiratory fitness, and blood pressure in patients with type 2 diabetes. This study had a quasi-experimental design and used purposive sampling. The samples consisted of 13 eligible patients with type 2 diabetes. Each subject underwent a 12-week exercise program (30 minutes a day, 3 days a week, and at 60% maximum oxygen uptake). Wilcoxon signed rank test was performed to examined pre- and post-training differences. At the end of the program, the results indicated that fasting blood glucose and fasting insulin were significantly decreased (p< 0.05); however, the HOMA-IR index, a valid estimate of insulin resistance, did not significantly change. Among serum lipids, total cholesterol, triglyceride and LDL also decreased significantly. Additionally, the cardiorespiratory fitness was elevated nearly 12.4% (p< 0.01). Furthermore, blood pressure was also improved (p< 0.01). It is concluded that exercise can improve insulin sensitivity, reduce serum lipids, increase cardiorespiratory fitness, and lower blood pressure in type 2 diabetes patients. ( J Rehab Med Assoc ROC 2003; 31(4): 207 - 215 )

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