This study describes a nursing experience of a tongue cancer patient who received radiation therapy after surgery and underwent dyspnea with endotracheal intubation, and followed by cardiac arrest, as well as the withdrawal of life-sustaining treatment after failing cardiopulmonary resuscitation and therapeutic hypothermia. The evaluation was based on Gordon's Eleven Functional Health Patterns and conducted from November 26 to December 8 in 2018, identified health issues include high-risk injury caused by therapeutic hypothermia, family decision anxiety, caregiver's anticipatory grief and so on. During the nursing process, strictly prevent hypothermia complications and the patient's condition was provided to ease decision-making anxiety and the sorrows of the family. The author feels by providing timely and adequate medical information for the decision makers will assist them to mitigate the pain when faced with the withdrawal life-sustaining treatment. It is hoped that by sharing this experience, this case can be served as a reference for the clinical nursing staff during the Shared Decision Making (SDM) between doctors and patients at the end of life caring requirement.