Nurse educators are encountering challenges in actual medical settings. Therefore, modifying current teaching strategies for enhancing the quality of nursing education has become an urgent concern. Based on the student-centered education model, the challenges that educators encounter typically involve modifying teaching strategies according to the needs and characteristics of learners. Nursing care of central venous catheters are important skills for oncology nurses. As the paradigm in healthcare nowadays is the evidence-based, patient-centered decision making, the issue of shared decision making (SDM) is highlighted in cancer care. We use the simulation and combine the SDM to teach new nurses. This paper aims to share the experience in clinical teaching for improving future nursing education.