腎上腺腺瘤造成之原發性皮質醛酮症

Primary Aldosteronism Caused by Aldosterone-Producing Adenoma

廖國盟(Kuo-Meng Liao)

《北市醫學雜誌》 2卷7期 (2005/07) Pp. 664-670

https://doi.org/10.6200/TCMJ.2005.2.7.10

摘要

五十多年，原發性皮質醛酮症由原來被認為稀有的疾病，現在發現可能是高血壓中可治癒的最常見的原因。而其在高血壓的病患中的盛行率，也由以往認為大約為0.5-2%，上升到5-10%左右。但一直為臨床醫師所忽略。本篇文獻報告一個案，因頑固性的高血壓、低血鉀及反覆性肌肉無力達三年之久。入院進行一系列內分泌檢查，發現是腎上腺腫瘤分泌過高之皮質醛酮所造成之原發性皮質醛酮症。經泌尿外科予以腹腔鏡腎上腺切除之後，病情痊癒。因此，僅以此個案報告，針對原發性皮質醛酮症作一個文獻回顧。

關鍵字

原發性皮質醛酮症 ； 腎上腺腺瘤 ； 血清皮質醛酮濃度

並列摘要

Primary aldosteronism is the most frequent, curable cause of hypertension. Since the introduction of new screening methods, the incidence rate among hypertensive patients has risen from between 0.05%-2% to between 5%-10%. However, it is frequently ignored by most clinicians. We report on a case presenting with refractory hypertension, hypokalemia and periodic paralysis over a three year period. Endocrine tests and image studies performed during hospitalization proved the presence of an aldosterone-producing adenoma. After laparoscopic adrenectomy, the hypertension and hypokalemia subsided.

並列關鍵字

aldosterone-producing adenoma ； plasma aldosterone concentration ； plasma renin activity ； primary aldosteronism