The Significance of Immunostains in Adenoid Cystic Carcinoma of Breast

免疫染色在乳房腺樣囊狀癌的重要性

陳嘉珮(Chia-Pei Chen) ； 林忠樹(Chung-Shu Lin) ； 周彥伶(Yen-Lin Chou)

《北市醫學雜誌》 7卷3期 (2010/09) Pp. 284-288

https://doi.org/10.6200/TCMJ.2010.7.3.10

摘要

乳房腺樣囊狀癌是一個罕見的腫瘍，佔所有乳腺惡性腫瘤不到千分之一。這類變體腺癌通常發生於唾液腺，不同於頭頸部腺樣囊狀癌的好侵犯性本質，乳房腺樣囊狀癌有較佳的預後，區分乳房腺樣囊狀癌及其它類型的乳癌很重要。我們報告一例六十五歲婦人，五年前曾發生子宮內膜癌，現在於左側乳房罹患腺樣囊狀癌p63及c-Kit的免疫染色陽性反應在正確診斷上扮演不可或缺的地位。

關鍵字

腺樣囊狀癌 ； 免疫染色 ； p63 ； c-Kit

並列摘要

Adenoid cystic carcinoma of the breast is a rare neoplasm, accounting for less than 0.1% of all mammary cancers. This variant of adenocarcinoma usually occurs in the salivary glands. Unlike the aggressive nature of adenoid cystic carcinoma in the head and neck, adenoid cystic carcinoma of the breast has a favorable prognosis. It is import to distinguish adenoid cystic carcinoma from other types of breast cancers. We report a 65-years-old woman with endometrioid carcinoma in uterus five years ago, and suffered from adenoid cystic carcinoma in left breast now. The positive immunostains of P63 and c-Kit play an integral role to make the correct diagnosis.

並列關鍵字

adenoid cystic carcinoma ； immunostains ； p63 ； c-Kit