Neonatal Abstinence Syndrome after Maternal Methadone Maintenance Treatment: A Case Report and Literature Review

母親孕期使用美沙酮戒毒引發新生兒戒斷症候群一病歷報告與文獻回顧

張峯榮(Feng-Jung Chang) ； 張祐剛(Yu-Kang Chang) ； 楊惠菁(Hui-Ching Yang) ； 侯沛蓁(Pei-Jen Hou) ； 繳君慧(Chun-Hui Chiao) ； 范洪春(Hueng-Chuen Fan)

《童綜合醫學雜誌》 13卷2期 (2019/12) Pp. 106-111

https://doi.org/10.3966/207135922019121302008

摘要

Neonatal abstinence syndrome (NAS) is a serious condition affecting newborns that typically occurs as a result of opioid withdrawal following prenatal opioid exposure. It generally manifests as a range of symptoms impacting the autonomic nervous system, gastrointestinal tract, and central nervous system. If left untreated or treated inappropriately, NAS can result in severe complications, including death. Here, we present a case involving a newborn with NAS born to a mother undergoing methadone maintenance treatment (MMT) for prior heroin use. The diagnosis and treatment of NAS among babies, as well as dilemmas associated with the promotion of MMT by governmental authorities, are also discussed.

關鍵字

Neonatal abstinence syndrome ； methadone maintenance treatment

並列摘要

新生兒戒斷症候群是一種因新生兒在胎兒時期暴露於鴉片類藥物的環境，隨出生後鴉片類藥物的終止，隨即出現會嚴重影響新生兒的情況。此症候群會表現出影響自主神經系統、腸胃道及中樞神經系統的症狀。如果不治療或處理不當，新生兒戒斷症候群可能會有嚴重的併發症，甚至是死亡。我們報告一個患有新生兒戒斷症候群的嬰兒，他的母親之前有使用海洛因，在懷孕前與懷孕期間接受美沙酮維持治療。本文將介紹由新生兒戒斷症候群的診斷與治療，以及討論美沙酮維持治療有關的困境。

並列關鍵字

新生兒戒斷症候群 ； 美沙酮維持治療