- 期刊
- OpenAccess
Extrarenal Wilms' Tumor of the Ovary: A Case Report
腎外的威爾姆氏卵巢腫瘤：病例報告
摘要
A primary extrarenal Wilms' tumor (ERWT) of the ovary is exceedingly rare. Here, the authors report the case of a 41-year-old woman who presented with lower abdominal pain and a palpable abdominal mass. Computed tomography examinations revealed a large solid mass located on the right side of her ovary and pelvic cavity. The patient was subsequently treated by surgical excision. Pathologic diagnosis of the neoplasm was ERWT of the ovary with a triphasic nephroblastoma comprising metanephric blastema, mesenchyme (stroma), and epithelial derivatives. In addition, the tumor occurred only in an extrarenal location without primary renal involvement. Immunohistochemical studies showed the tumor cells were positive for Wilms' tumor-associated protein 1, vimentin, and CD56, and were negative for CD99, estrogen receptor, progesterone receptor, smooth muscle actin, and S100. The patient was administered adjuvant chemotherapy according to recommendations from the National Wilms' tumor study and continued to be followed up for survival.
並列摘要
原發性腎外的威爾姆氏卵巢腫瘤非常罕見。我們報告一名41歲女性患者的病例，該女性因下腹部疼痛與可觸及的腹部腫塊而前來就診。電腦斷層掃描（CT）檢查顯示位於卵巢和骨盆腔右側出現巨大實質腫塊。經手術切除的腫瘤病理切片診斷此二腫塊皆為腎外腎母細胞瘤（ERWT）－因其具有包括胚基，間質（基質）和上皮衍生物的三相腎母細胞瘤組織。此外，腫瘤僅發生在沒有原發性腎臟轉移的腎外位置。免疫組織化學染色的結果顯示腫瘤對WT1、Vimentin與CD56呈陽性，對CD99、ER、PR、SMA與S100呈陰性。目前正依據威爾姆氏腫瘤研究小組（NWTS）所建議的治療方針對患者進行輔助化療，並持續進行追蹤中。
延伸閱讀
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